Regulated cell death (RCD) is a special form of regulated cell death caused by the activation of one or more signal transduction modules, which is important for maintaining biological balance and intracellular homeostasis.

Through collection and screening 2180 published literatures and searching according to key words, RCDdb has recorded 11 known and 4 newly reported death types, a total of 1850 RCD genes, including 1604 coding genes and 246 non-coding genes and evidence description of the experiment. RCDdb also provides annotation of different types of RCD genes, including disease, drug, pathway, clinical, mutation, expression and interaction network. In addition, RCDdb provides three RCD-based online analysis tools: 1) Enrichment analysis of user's interested genes to the RCDdb reference gene sets. 2) Screening signature RCD genes by three machine learning algorithms. 3) Gene set scoring analysis by GSVA and ssGSEA method. RCDdb is a powerful platform that provides a variety of types of RCD gene sets, annotations and analysis based RCD gene sets for users.